The epidemiological studies that have been published to date detail a multitude of congenital defects that may be associated with the use of Paxil during pregnancy. Those discussed include cardiac, cranio-facial, skeletal and other birth defects. GSK has claimed that there is no pattern to whatdefects are alleged to be caused by Paxil.

This is incorrect. All of the deformities cited in the studies are related to neural crest cells and neural crest cell migration.

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